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橄榄油与动脉功能

能救命的营养学 蔬食益生 2023-06-04

本视频由Michael Greger医生于 2015 年 8 月 17 日发布,来自NutritionFacts.org — 能救命的营养学。


   如何从各种相互矛盾的有关营养与疾病的信息中找到靠谱的信息?(点击了解)

 

Michael Greger 医生是畅销书《How Not to Die》一书作者,中文译本:繁体版书名为《食疗圣经》。简体版书名为《救命》,于今年5月底出版。




橄榄油与动脉功能

Olive Oil & Artery Function




 

摘要:特级初榨橄榄油是否象精炼油和动物脂肪一样,具有相同的对动脉功能的不利影响?

Does extra virginolive oil have the same adverse effect on arterial function as refined oils and animal fats?

 

https://v.qq.com/txp/iframe/player.html?vid=k06814kxkas&width=500&height=375&auto=0


动脉相对麻痹出现于吃快餐和芝士蛋糕后数小时,吃橄榄油后也会出现。

The relative paralysis of our arteries for hours after eating fast food and cheesecake may also occur after olive oil.

 

橄榄油与其他高脂肪膳食一样具有相同的对血管内皮功能的损害。香肠和蛋McMuffin是最糟糕的,但橄榄油也差不了多少。

Olive oil was found to have the same impairment to endothelial function as the rest of these high-fat meals. Sausage and Egg McMuffin was the worst, but olive oil wasn’t far behind.


 

研究表明,摄取橄榄油后对血管内皮的好处已经测量出不同的结果 - 缺血诱导的,与血流介导的内皮依赖性血管舒张功能相对比 - 并没有很好的证据表明,这实际上是血管内皮功能的指标,这是预测心脏疾病的指标。数百项研究表明,测试可能会带来假阴性结果。

Studies that have suggested endothelial benefits after olive oil consumption have measured something different — ischemia-induced, as opposed to flow-mediated dilation — and there’s just not good evidence that that’s actually an index of endothelial function, which is what predicts heart disease. Hundreds of studies have shown that this other test can give a false negative result.

 

但是,这不仅仅是橄榄油。 其他油类也显示对血管内皮功能有不良影响 - 每次餐后3小时内皮功能显著且持续降低,与油的类型无关,以及与油是否新鲜还是油炸的无关。

But, it’s not just olive oil. Other oils have also been shown to have deleterious effects - a significant constant decrease in endothelial function three hours after each meal, independent of the type of oil, or whether the oil was fresh or deep fried.



橄榄油可能比富含ω-6脂肪酸或饱和脂肪更好,但仍表现出不利影响。然而,这项研究是用普通的精炼橄榄油完成的。那么特级初榨橄榄油呢?

Olive may be better than omega-6-rich oils, or saturated fats, but still showed adverse effects. But this study was done on regular refined olive oil. What about extra virgin?

 

特级初榨橄榄油保留橄榄果实中发现的一小部分抗炎植物营养素,因此似乎不会诱发由普通橄榄油引起的炎症标志物的峰值。但是这对我们的动脉意味着什么?

Extra virgin olive oil retains a fraction of the anti-inflammatory phytonutrients found in the olive fruit, and so it does not appear to induce the same kind of spike in inflammatory markers caused by regular olive oil. But what does that mean for our arteries?


  

与牛油相比,特级初榨橄榄油可能具有更多的中性作用,牛油发挥的有害作用持续长达六个小时 - 基本上直到下一顿饭。

Extra virgin olive oil may have more of a neutral effect, compared to butter, which exerted a noxious effect that lasted for up to six hours — basically right up to our next meal.

 

在有史以来最大的前瞻性研究中去评估摄取橄榄油与心脏事件如心脏病发作之间的关系,发现初榨橄榄油可能比普通橄榄油好,但是在对照核实健康的饮食行为(如蔬菜摄取量)后,两者均未发现显著降低心脏病发作率,因蔬菜往往同时与橄榄油一起食用。

In the largest prospective study ever to assess the relationship between olive oil consumption and cardiac events, like heart attacks, there was a suggestion that virgin olive oil may be better than regular olive oil, but neither were found to significantly reduce heart attack rates after controlling for healthy dietary behaviors like vegetable intake, which tends to go hand-in-hand with olive oil intake.

 

然而有研究发现,与预期相反,即使是特级初榨橄榄油也可能显著损害血管内皮功能。

There have been studies, though, showing even extra virgin olive oil, contrary to expectations, may significantly impair endothelial function as well.


(图中英文翻译:目前研究。与假设部分相反,研究发现富含omega-9【油酸】的橄榄油在餐后会损害血管内皮功能。)


那么为什么有些研究表明采取地中海式饮食(一种富含橄榄油的饮食),人们的血管内皮功能会改善呢?

So why do some studies suggest people’s endothelial function improves on a Mediterranean diet, a diet rich in olive oil?

 

也许是因为它还含有丰富的全谷物、水果、蔬菜、豆类和核桃。

Perhaps because it’s also rich in whole grains, fruits, vegetables, beans, and walnuts, as well.

 


饮食中的水果和蔬菜似乎提供了一些保护,抵抗高脂肪食物(包括橄榄油)产生的血管内皮功能的直接损害。

Dietary fruits and vegetables appear to provide some protection against the direct impairment on endothelial function produced by high-fat foods, including olive oil.

 

所以,健康状况的改善可能与油有关,却不是因为油。

So, improvements in health may be in spite of, rather than because of, the oil.



就其对餐后血管内皮功能(饭后)的影响而言,地中海式饮食的有益成分可能主要是富含抗氧化剂的食物 - 蔬菜、水果及其衍生物,例如巴萨米克香醋。

In terms of their effects on postprandial endothelial function (after a meal), the beneficial components of the Mediterranean diet may primarily be the antioxidant-rich foods — the vegetables, fruits, and their derivatives, such as balsamic vinegar. 


只要在高脂肪餐食中加入一些蔬菜可能会部分恢复动脉功能和血流量。

Just adding some vegetables to a fatty meal may partially restore arterial functioning and blood flow.


(翻译及字幕制作:老玉米 Karen Chou)


参考文献:

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  2. RA Vogel, MC Corretti, GD Plotnick. The postprandial effect of components of the Mediterranean diet on endothelial function. J Am Coll Cardiol. 2000 Nov 1;36(5):1455-60.

  3. CF Rueda-Clausen, FA Silva, MA Lindarte, C Villa-Roel, E Gomez, R Gutierrez, C Cure-Cure, P López-Jaramillo. Olive, soybean and palm oils intake have a similar acute detrimental effect over the endothelial function in healthy young subjects. Nutr Metab Cardiovasc Dis. 2007 Jan;17(1):50-7.

  4. K Esposito, R Marfella, M Ciotola, C Di Palo, F Giugliano, G Giugliano, M D'Armiento, F D'Andrea, D Giugliano. Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA. 2004 Sep 22;292(12):1440-6.

  5. RA Vogel. Brachial artery ultrasound: a noninvasive tool in the assessment of triglyceride-rich lipoproteins. Clin Cardiol. 1999 Jun;22(6 Suppl):II34-9.

  6. F Fuentes, J López-Miranda, P Pérez-Martínez, Y Jiménez, C Marín, P Gómez, JM Fernández, J Caballero, J Delgado-Lista, F Pérez-Jiménez. Chronic effects of a high-fat diet enriched with virgin olive oil and a low-fat diet enriched with alpha-linolenic acid on postprandial endothelial function in healthy men. Br J Nutr. 2008 Jul;100(1):159-65.

  7. N Tentolouris, C Arapostathi, D Perrea, D Kyriaki, C Revenas, N Katsilambros. Differential effects of two isoenergetic meals rich in saturated or monounsaturated fat on endothelial function in subjects with type 2 diabetes. Diabetes Care. 2008 Dec;31(12):2276-8.

  8. M Ryan, D McInerney, D Owens, P Collins, A Johnson, GH Tomkin. Diabetes and the Mediterranean diet: a beneficial effect of oleic acid on insulin sensitivity, adipocyte glucose transport and endothelium-dependent vasoreactivity. QJM. 2000 Feb;93(2):85-91.

  9. EA Miles, P Zoubouli, PC Calder. Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures. Nutrition. 2005 Mar;21(3):389-94.

  10. F Fuentes, J López-Miranda, E Sánchez, F Sánchez, J Paez, E Paz-Rojas, C Marín, P Gómez, J Jimenez-Perepérez, JM Ordovás, F Pérez-Jiménez. Mediterranean and low-fat diets improve endothelial function in hypercholesterolemic men. Ann Intern Med. 2001 Jun 19;134(12):1115-9.

  11. P Bogani, C Galli, M Villa, F Visioli. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. Atherosclerosis. 2007 Jan;190(1):181-6.

  12. R Moreno-Luna, R Muñoz-Hernandez, ML Miranda, AF Costa, L Jimenez-Jimenez, AJ Vallejo-Vaz, FJ Muriana, J Villar, P Stiefel. Olive oil polyphenols decrease blood pressure and improve endothelial function in young women with mild hypertension. Am J Hypertens. 2012 Dec;25(12):1299-304.

  13. K Esposito, F Nappo, F Giugliano, G Giugliano, R Marfella, D Giugliano. Effect of dietary antioxidants on postprandial endothelial dysfunction induced by a high-fat meal in healthy subjects. Am J Clin Nutr. 2003 Jan;77(1):139-43.

  14. T Gori. Olive oil and ischemic reactive hyperemia in hypercholesterolemic patients. J Am Coll Cardiol. 2006 Jul 18;48(2):414; author reply 414-5.

  15. J Ruano, J Lopez-Miranda, F Fuentes, JA Moreno, C Bellido, P Perez-Martinez, A Lozano, P Gómez, Y Jiménez, F Pérez Jiménez. Phenolic content of virgin olive oil improves ischemic reactive hyperemia in hypercholesterolemic patients. J Am Coll Cardiol. 2005 Nov 15;46(10):1864-8.

  16. G Buckland, N Travier, A Barricarte, E Ardanaz, et al. Olive oil intake and CHD in the European Prospective Investigation into Cancer and Nutrition Spanish cohort. Br J Nutr. 2012 Dec 14;108(11):2075-82.





译后记:


经常看到这样的沙拉菜谱,把本是健康的沙拉加上两大匙橄榄油。心里就会直叫:可惜呀可惜!


另外,还记得这篇文章吗?


当心脏病无法手术治疗时,唯一的救命稻草是什么?


老玉米只把两张图放在这里:

埃塞斯廷医生苦口婆心劝大家不要用油煮菜。

心脏堵塞的血管在采纳“低脂全蔬食”后疏通。



更多关于油的文章:


椰子油到底有益还是有害?请看2018年最新研究:椰子油与腹部脂肪


椰子油是有害的,那么椰子和椰奶呢?




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德国美女大学生 丽萨 用中文特别推荐符合 “低脂全蔬食” 原则的健康食谱公众号


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关于编译者老玉米是美国康奈尔大学坎贝尔营养研究中心《蔬食营养》证书持有者。老玉米的先生是美国内科医生(MD),也是位“蔬食医生”(Plantrician)。

 

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